Thursday, October 2, 2008

2% CHLORHEXIDINE DIGLUCONATE

The success of endodontic treatment is directly influenced by elimination of microorganisms in infected root canals.
With apical periodontitis, effective antimicrobial agents are necessary.
The irrigant solutions are very important during root canal preparation because they aid in the cleaning of the root canal, lubricate the files, flush out debris, and have an antimicrobial effect and tissue dissolution, without damage to periapical tissues.
The selection of an ideal irrigant depends on its action on microorganisms and periapical tissues.


Chlorhexidine is a cationic agent (biguanide group; 4-chlorophenyl radical), which exhibits antibacterial activity.
The cationic nature of the compound promotes connection with anionic compound at the bacterial surface (phosphate groups from teicoic acid at Gram-positive and lipopolysaccharide at Gram-negative bacteria) capable of altering its integrity.
The potassium ion, being a small entity, is the first substance to appear when the cytoplasmic membrane is damaged.
The alteration of the cytoplasmic membrane permeability promotes precipitation of cytoplasmic proteins, alters cellular osmotic balance, interferes with metabolism, growth, cell division, inhibits the membrane ATPase and inhibits the anaerobic process.


DENTOCHLOR: 2% Chlorhexidine Solution for Dental Irrigation & as Root Canal Disinfectant

As efficient Antibacterial for Intracanal Medicament
Including E.Fecalis, which is always found in failure cases

0.5ml per Canal

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